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More robust CYP3A4 inhibitors including ketoconazole or itraconazole can be predicted to possess larger effects than witnessed with saquinavir. A commencing dose of 25 mg of VIAGRA needs to be deemed in sufferers getting erythromycin or potent CYP3A4 inhibitors (like saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRATION, CLINICAL P